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The support program that helps get you started on KYNMOBI

Once your doctor has decided KYNMOBI is right for you, they may enroll you in our support program, KYNMOBI® KYNNECT, which is here to ensure that you are prepared to start treatment

Your KYNMOBI® KYNNECT Support Team will consist of:

Clinical Educator icon

Clinical Educator:

Works with you to navigate the process of finding the right dose, at home or virtually, and provide updates to your doctor. A Clinical Educator may not be needed if your doctor chooses to work directly with you

KYNMOBI® KYNNECT Case Manager icon

KYNMOBI® KYNNECT Case Manager:

Dedicated to answering any questions, ensuring prompt delivery of KYNMOBI, and exploring ways to save money on your prescription

What to expect when enrolled in KYNMOBI® KYNNECT:

Icon with a faceless person along with a to-do list

1

Starting With KYNMOBI® KYNNECT

  • After your doctor enrolls you in KYNMOBI® KYNNECT, you will receive a consent form via text and email. You must confirm consent before you can get started
  • Within 2 days of receiving your consent, your Case Manager will give you a welcome call to explain next steps and discuss your best financial options for KYNMOBI
  • Your Case Manager will coordinate delivery of a KYNMOBI Starter Kit to your home (if needed), which will include a range of dose strengths
A prescription sheet next to a vial

2

Finding Your Personalized Dose

  • With support, you will use your Starter Kit to see how you respond to a range of dose strengths, increasing it gradually to help you identify which dose is right for you
  • Determining your personalized dose can take place over a series of visits to the doctor’s office or with a Clinical Educator from the comfort of your home
  • Once you’ve determined your right dose, your doctor will write you a prescription for KYNMOBI
Closed box next to a check mark

3

Your First Prescription

  • Now that your right dose has been identified, your KYNMOBI® KYNNECT Support Team will ensure that your doctor writes your prescription. Based on your preferences, your prescription will be delivered to your door or sent to your local pharmacy for pickup
  • If you are assigned a Clinical Educator, you will receive a follow-up call 2 weeks after you receive your prescription to see how your treatment is going
Prescription sheet with a calendar icon

4

Refilling Your Prescription

  • Your KYNMOBI® KYNNECT Support Team will stay connected, sending you refill reminders and helping you navigate any changes to your insurance coverage so that you’re never without your KYNMOBI prescription
Hand holding KYNMOBI film

Your KYNMOBI® KYNNECT Support Team will stay engaged from the initial welcome call all the way through the delivery of your prescription refills

Additional support to meet your needs

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Quick FAQs about KYNMOBI

See frequently asked questions about KYNMOBI

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KYNMOBI Savings Program

Navigate insurance and copay
questions with
a trained representative.


Questions?
Call us at 1-844-KYNMOBI (1-844-596-6624), Monday through Friday, 8 AM–8 PM ET

IMPORTANT SAFETY INFORMATION AND INDICATION FOR KYNMOBI (apomorphine HCI) SUBLINGUAL FILM

Do not take KYNMOBI if you are taking certain medicines to treat nausea called 5HT3 antagonists, including ondansetron, granisetron, dolasetron, palonosetron, and alosetron. People taking ondansetron together with apomorphine, the active ingredient in KYNMOBI, have had very low blood pressure and lost consciousness or "blacked out."

Do not use KYNMOBI if you are allergic to apomorphine hydrochloride or to any of the ingredients in KYNMOBI. KYNMOBI also contains a sulfite called sodium metabisulfite. Sulfites can cause severe, life‐threatening allergic reactions in some people. An allergy to sulfites is not the same as an allergy to sulfa. People with asthma are more likely to be allergic to sulfites. Call your healthcare provider if you have hives, itching, rash, swelling of the lips, tongue and mouth, redness of your face (flushing), throat tightness, trouble breathing or swallowing.

Before starting KYNMOBI, tell your healthcare provider:

About all of your medical conditions, including if you:

  • have difficulty staying awake during the daytime
  • have liver problems
  • have dizziness
  • have kidney problems
  • have fainting spells
  • have heart problems
  • have low blood pressure
  • have had a stroke or other brain problems
  • have asthma
  • have a mental problem called a major psychotic disorder
  • are allergic to any medicines containing sulfites
  • drink alcohol
  • are pregnant or plan to become pregnant. It is not known if KYNMOBI will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if KYNMOBI passes into your breast milk. You and your healthcare provider should decide if you will take KYNMOBI or breastfeed.

Tell your healthcare provider about all the medicines you take, including:

  • prescription medicines
  • over-the-counter medicines
  • vitamins
  • herbal supplements

KYNMOBI may affect the way other medicines work, and other medicines can affect how KYNMOBI works. Taking KYNMOBI with other medicines may cause serious side effects.
If you take nitroglycerin under your tongue (sublingual) while using KYNMOBI, your blood pressure may decrease and cause dizziness. You should lie down before and after taking sublingual nitroglycerin.

KYNMOBI can cause serious side effects, including:

  • nausea and vomiting. Nausea is a common side effect of KYNMOBI. Nausea and vomiting can happen with KYNMOBI. Your healthcare provider may prescribe a medicine called an antiemetic, such as trimethobenzamide to help prevent nausea and vomiting. If trimethobenzamide is prescribed, talk to your healthcare provider about how long you should remain on this medicine.
  • sleepiness or falling asleep during the day. Sleepiness is a serious, and common side effect of KYNMOBI. Some people treated with KYNMOBI may get sleepy during the day or fall asleep without warning while doing everyday activities such as talking, eating, or driving a car.
  • dizziness. Dizziness is a serious, and common side effect of KYNMOBI. KYNMOBI may lower blood pressure and cause dizziness. Dizziness can happen when KYNMOBI treatment is started or when the KYNMOBI dose is increased. Do not get up too fast from sitting or after lying down, especially if you have been sitting or lying down for a long period of time.
  • mouth (oral) irritation. Mouth (oral) irritation is a common side effect of KYNMOBI. You should call your healthcare provider if you develop any of these signs or symptoms:
    • redness
    • mouth sores (ulceration)
    • dryness of the mouth, lips or tongue
    • swelling
    • pain
    • pain with swallowing
  • falls. The changes that can happen with PD, and the effects of some PD medicines, can increase the risk of falling. KYNMOBI may also increase your risk of falling.
  • hallucinations or psychotic-like behavior. KYNMOBI may cause or make psychotic-like behavior worse including hallucinations (seeing or hearing things that are not real), confusion, excessive suspicion, aggressive behavior, agitation, delusional beliefs (believing things that are not real), and disorganized thinking.
  • low red blood cells (hemolytic anemia). Tell your healthcare provider if you have any of the following signs or symptoms:
    • you become pale
    • skin or eyes look yellow
    • chest pain
    • dizziness
    • fever
    • dark-colored urine
    • fast heartbeat
    • feel more tired or weaker than usual
    • shortness of breath or trouble breathing
    • confusion
  • strong (intense) urges. Some people with PD have reported new or strong uncontrollable urges to gamble, increased sexual urges, increased urges to spend money (compulsive shopping), and other intense urges, while taking PD medicines, including KYNMOBI. If you or your family members notice that you have strong urges, talk to your healthcare provider. The strong urges may go away if your KYNMOBI dose is lowered or stopped.
  • high fever and confusion. KYNMOBI may cause a problem that can happen in people who suddenly lower their dose, stop using, or change their dose of KYNMOBI. Symptoms include:
    • very high fever
    • confusion
    • stiff muscles
    • changes in breathing and heartbeat

    Do not stop taking KYNMOBI or change your dose unless you are told to do so by your healthcare provider.

  • heart problems. If you have shortness of breath, fast heartbeat, chest pain, or feel like you are going to pass out (faint) while taking KYNMOBI, call your healthcare provider or get emergency help right away.
  • tissue changes (fibrotic complications). Some people have had changes in the tissues of their pelvis, lungs, and heart valves when taking medicines called nonergot derived dopamine agonists like KYNMOBI.
  • prolonged painful erections (priapism). KYNMOBI may cause prolonged, painful erections in some people. If you have a prolonged and painful erection, you should call your healthcare provider or go to the nearest hospital emergency room right away.

The most common side effects of KYNMOBI include:

  • nausea
  • dizziness
  • sleepiness
  • mouth swelling, pain, or sores

INDICATION

KYNMOBI® (apomorphine HCl) sublingual film is a prescription medicine used to treat short-term (acute), intermittent “off” episodes in people with Parkinson’s disease (PD).

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For more information, please see the KYNMOBI Patient Information, full Prescribing Information, and Instructions for Use.